Wegovy Doses and Titration Calendar Explained

Everyone starts Wegovy on the same beginner dose of 0.25mg. But from that point onwards, your journey becomes your own. You’ll work with your clinician to decide whether to increase your dose (known as titration) or stick to your current levels.

We’ll explain what your Wegovy dosing schedule might look like, how you’ll know you’re ready for the next dose up, and whether you actually need to increase how much Wegovy you take.

Three key takeaways

  • Your schedule is designed to gently introduce the medicine to your body, giving you plenty of time to adjust comfortably to each new dose.
  • You don't have to race to the maximum dose. Sticking to a lower amount is absolutely fine if it works for you.
  • You and your clinician will decide your titration calendar together. They’ll help you figure out exactly what safe, effective dosing looks like for you.

Wegovy dosing schedule

What doses of Wegovy are available?

There are six licensed doses of Wegovy currently available:

  • 0.25mg, which is a starter dose to help you get used to the medication
  • 0.5mg
  • 1mg
  • 1.7mg
  • 2.4mg
  • 7.2mg, which is the maximum dose available

Do you lose more weight at higher doses of Wegovy?

A recent clinical trial called STEP-UP found that Wegovy 7.2mg resulted in average weight loss of 21%.

In comparison, patients on the 2.4mg dose achieved average weight loss of 17% during the STEP 4 trial.

However, everyone responds to Wegovy differently. For example, you might find the 2.4mg dose easier to tolerate while still achieving the weight-loss results you need.

How many doses are in one Wegovy pen?

Each Wegovy pen contains four doses to be injected once a week. However, if you’re on Wegovy 72.mg, you'll need to take three 2.4mg injections once a week, as a single 7.2mg pen isn’t yet available.

Weekly Wegovy dosage calendar

Everyone’s Wegovy dosing calendar is going to look different. You’re under no pressure to increase your dose, and you’ll only titrate up when you and your clinician agree it’s right for you.

To give you an idea of what you can expect, we’ve put together a typical 20-week dosing calendar, taking you from 0.25mg all the way to 2.4mg and beyond.

  • Weeks 1-4: your starter dose of 0.25mg
  • Weeks 5-8: increase to 0.5mg
  • Weeks 9-12: increase to 1mg
  • Weeks 12-16: increase to 1.7mg
  • Weeks 17-20: increase to 2.4mg
  • Beyond week 20: increase to maximum dose of 7.2mg

Knowing when to inject Wegovy, when in your cycle to request a new pen, and what your increased dose schedule might look like can all help you plan your treatment journey and manage titration.

Be sure to increase your dose under medical supervision. Your clinician can track the effects of your medication on your weight loss journey, help you manage side effects, and work out the most effective dose for you.

Weekly Wegovy dose schedule

When to increase your dose of Wegovy

You should spend at least four weeks on your current dose before considering an increase. This helps your body adjust to the medication and allows you to decide whether it’s an effective dose for your weight-loss journey.

While you don’t have to increase your dose after four weeks, signs that you might be ready include:

  • you're handling any side effects well
  • you're still experiencing food cravings
  • you've not reached your target weight

You should only consider increasing your dose when you’re ready and if a clinician agrees that you’re at the right point in your treatment plan.

“Clinical trials have shown greater weight loss at higher doses, but that’s not the whole picture. Your body is your own, and you’ll lose weight at an entirely different rate than someone else.

“We’ll consider several factors when deciding whether you’re suitable for a dose increase, including whether you’re losing weight, how it makes you feel, and what you’re eating while on a lower dose.

“What matters most is the journey toward better health and well‑being, not the specific number on the scale. We’re here to support you every step of the way, helping you feel confident, motivated, and safe, while advising you on the most suitable medication and dosage to help you reach your health goals.”

Jason Murphy, Head of Pharmacy at Chemist4U

Jason Murphy

How to increase your Wegovy dosage

When you’re thinking about increasing your Wegovy dose, don’t simply double-dose using your existing medication. You need to book a new consultation with your prescriber to discuss the potential side effects and whether it’s the right choice for you.

Once you both decide you’re ready to increase your Wegovy dose, your clinician will move you to the next available dose. For example, you wouldn’t go straight from 0.5mg to 1.7mg. Instead, you’d try out 1mg for four weeks to see how it affects you.

Do you have to increase your dose?

You don’t have to increase your dose. Everyone is different, and some people get the results they want from the starter dose. Others might need to move up to the 7.2mg dose for the full effect.

A clinician will look at side effects and the amount of weight you’re losing and work with you to determine whether a higher dose will be safe and effective for you.

The aim of the titration phase is to find a comfortable maintenance dose that gives you results supported by a healthy diet and regular movement, rather than keeping you on more and more Wegovy each month.

What to expect when increasing your dose

It’s more than use your pen that changes when you increase your dose:

Relationship with food

When you move from one dose to another, you may find that:

  • your appetite reduces
  • your food noise continues to quieten
  • you feel fuller faster, and for longer

Because of these changes, it’s really useful to have a Wegovy diet plan in place. Not only will it help you build healthier habits, it’ll also allow you to make sure you’re getting the nutrition you need as your appetite changes.

Weight loss

You may find that, as your dose increases, so does your weight loss. For example, a clinical trial found that increasing the dose from 1 mg to 2.4 mg led to an average of 5-6% more weight loss than the lower dose. So, if you and your clinician agree that you’re ready for a higher dose, it could lead to greater weight-loss benefits.

Side effects

Every time you increase your dose, you may encounter the Wegovy side effects you experienced when you first started.

The good thing is the same methods you used to tackle them the first time should still work. So, make sure to stock up the things you found helped you manage your side effects the week of your titration, whether that’s ginger tea for nausea or treatments for diarrhoea.

Cost

The price of Wegovy gradually increases alongside your dose. At Chemist4U, the 0.25mg costs £99 a month, up to £279 a month for Wegovy 7.2mg. You may, therefore, need to factor in cost when you’re deciding whether or not to increase your dose.

What is the maximum dose of Wegovy?

The maximum dose of Wegovy is 7.2mg.

Until recently, 2.4mg was the maximum dose available. However, as of 2026, the Medicines and Healthcare products Regulatory Agency (MHRA) has approved a maximum weekly dose of 7.2 mg. This is currently available as three 2.4 mg injections, taken weekly, rather than a single jab.

Taking 7.2 mg Wegovy may increase your risk of side effects, including digestive issues and dysaesthesia, a sensation which feels like a burning on the skin. However, as with other doses of Wegovy, these side effects are often mild and usually resolve quickly.

Wegovy dosages vs other weight loss drugs

If you’ve taken other weight loss drugs, you might be used to different doses or numbers of pens. Here’s how the different weight loss medications stack up in terms of what you get in a pack and how often you take them:

MedicationFrequencyPen typeDoses per PenStandard pack sizeAvailable doses
WegovyWeeklyMulti-use  4 doses - One pen lasts 4 weeks)1 pen0.25mg
0.5mg
1mg
1.7mg
2.4mg
7.2mg
MounjaroWeeklyMulti-use4 doses - One pen lasts 4 weeks)1 pen2.5mg
5mg
7.5mg
10mg 12.5mg 15mg
SaxendaDailyMulti-use, as it’s “Dial-a-dose,” meaning you choose the dose in line with prescriber recommendationsVaries, but 6 doses at full 3.0mg5 pens0.6mg
1.2mg 1.8mg 2.4mg
3mg

Why are Wegovy doses lower than Mounjaro?

Wegovy doses are lower than Mounjaro because they’re different medications. Researchers have examined how each medication works and recommended the safest dose that produces the desired effect on weight loss.

Mounjaro doses range from 2.5mg to 15mg, while Wegovy ranges from 0.25mg to 7.2mg. However, a lower dose doesn’t mean that Wegovy is more potent. It just works differently.

How our expert team of clinicians can help

If you have any questions about increasing your dose of Wegovy, dealing with side effects, or when to know if you’ve found your maintenance dose, our expert clinicians are here to help.

Frequently asked questions about Wegovy doses

Is there a big difference between Wegovy 1.7mg and 2.4mg?

Wegovy 2.4mg is stronger than 1.7mg, and some people might find that it leads to more significant weight loss results. However, you don’t have to move up if you and your clinician agree that you’re tolerating 1.7mg well and seeing results that improve your health.

How many months does four pens of Wegovy cover?

Four Wegovy pens would last you 16 weeks, with each pen containing four doses. You’d take one dose per week. You can store a Wegovy pen in the fridge until the expiry date.

Is it better to inject Wegovy in the morning or at night?

You can take Wegovy at any time of day, before or after eating food. Choose one that suits your schedule and lifestyle. However, if you can, try to take Wegovy on the same day each week.

Sources

Jason Murphy - Head of Pharmacy
Jason Murphy , Head of Pharmacy on 13 February 2026
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