Pancreatic Enzyme Replacement Therapy (PERT)
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Pancreatic Enzyme Replacement Therapy (PERT)

Pancreatic insufficiency is a condition where the pancreas does not produce enough of the enzymes needed for proper digestion.

These enzymes, including lipase, protease, and amylase, are essential for breaking down fats, proteins, and carbohydrates in food.

Without sufficient enzymes, the body cannot effectively absorb nutrients, leading to symptoms such as weight loss, diarrhoea, fatty stools (steatorrhea) and malnutrition.

Pancreatic insufficiency can result from conditions like chronic pancreatitis, cystic fibrosis, pancreatic cancer, or after surgical removal of part of the pancreas. Treatment can involve Pancreatic Enzyme Replacement Therapy (PERT) to help with digestion and nutrient absorption.

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Pancreatic Enzyme Replacement Therapy (PERT) Treatments

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Alexandra Moses - Medical Content Writer
Alexandra Moses
Medical Content Writer
28/05/2024
27/05/2026
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist
28/05/2024

How does Pancreatic Enzyme Replacement Therapy (PERT) work?

Pancreatic Enzyme Replacement Therapy (PERT) helps people with pancreatic insufficiency, where their pancreas can't produce enough digestive enzymes.

PERT involves taking enzyme supplements with meals to aid digestion. These supplements contain enzymes like lipase, protease, and amylase, which break down fats, proteins and carbohydrates.

This treatment improves nutrient absorption, reducing symptoms like weight loss and diarrhoea.

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